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Showing posts with label Gene tests. Show all posts
Showing posts with label Gene tests. Show all posts

Friday, July 8, 2016

Donie's Ireland daily news BLOG update

Former Labour Court chair to lead water commission

SIMON COVENEY TO APPOINT KEVIN DUFFY AS CHAIRMAN AFTER JOE O’TOOLE’S RESIGNATION

   
Former Labour Court chairman Kevin Duffy is to lead the expert commission examining the future of water charges in the State.
Minister for Housing Simon Coveney is to appoint Mr Duffy to replace Joe O’Toole, who was forced to resign this week after a series of controversial interviews.
Mr O’Toole, a former senator, said he believed water must be paid for and that he supported the polluter pays principle. He blamed Fianna Fáil for his resignation, insisting he had retained the support of Mr Coveney despite his comments.
“That was until Minister Coveney informed me that the main Opposition party would not co-operate with Government on this and related issues for as long as I remained in the chair,” he said.
Mr Duffy, who is a former assistant general secretary of the Irish Congress of Trade Unions, has been chosen to replace him. It is understood Mr Coveney informed Taoiseach Enda Kenny and Fianna Fáil of the decision on Thursday.
The seven member commission is examining the future of water charges and has five months to report back to an Oireachtas committee which will then vote on its recommendations.
Mr Coveney is to travel to Brussels on Friday to meet environment commissioner Karmenu Vella to explain the decision to suspend water charges for nine months.
The Minister and Mr Vella have been in contact but Mr Coveney is expected to stress the rationale behind the agreement reached with Fianna Fáil which underpinned the formation of a minority government.
The meeting follows an instruction issued by the European Commission that Ireland cannot revert to the position of not paying for water.

Tánaiste Fitzgerald agrees to accept more refugees into Ireland

    

A SELECTION TEAM WILL BE SENT TO LEBANON TO SELECT AN ADDITIONAL 260 REFUGEES UNDER THE REFUGEE RESETTLEMENT PROGRAMME, TÁNAISTE AND MINISTER FOR JUSTICE AND EQUALITY, FRANCES FITZGERALD CONFIRMED TODAY.

“I am pleased to confirm that the Refugee Resettlement Strand of the Programme has seen significant progress,” the Tánaiste said.
“Two hundred and seventy three refugees have already arrived from Lebanon and the remainder of the 520 refugees we committed to resettle in Ireland in 2016 will be here by the autumn.
“This is in advance of the EU deadline and clearly demonstrates Ireland’s continued proactive approach to resolving this unprecedented humanitarian crisis.
“Yesterday I informed the Government of my decision to send a further mission to Lebanon in the autumn to select an additional 260 refugees to be admitted in Spring 2017.”
The decision by the Tánaiste to increase the number of refugees to arrive in Ireland under the Resettlement Strand of the IRPP takes account of the slower than anticipated arrival of asylum seekers from Greece and Italy as a result of administrative issues in those countries.
“My decision reflects the Government’s commitment to welcome vulnerable refugees fleeing war and conflict and is another positive step towards delivering on Ireland’s overall commitment to accept 4,000 persons,” she said.
“Once in Ireland, these refugees will have access to vital health and education services. Our focus will be on helping them to rebuild their lives here in Ireland.”
She added: “A further 28 Syrians arrived in Ireland in the last couple of weeks under relocation from Greece.
“I am aware that progress regarding the relocation of persons from Italy and Greece has been slower than we would have wanted but this should not be taken as any diminution of our commitment to delivering on this part of the programme.
“The delay has been largely outside of our control and my officials have been working closely with their Greek and Italian counterparts on this issue.
“The Greek authorities have now agreed that they will double the numbers available for transfer to Ireland to 40 persons every four weeks with the prospect of this number increasing further later in the year. In effect this means that the relocation strand will now be fully operational.”

Troubled suicide charity Console is to be wound down and transferred to other support services? 

   
David Hall (left pic) who was installed last week to try to rescue the charity and Paul Kelly right.

THE TROUBLED SUICIDE BEREAVEMENT CHARITY CONSOLE IS TO BE WOUND DOWN.

The charity’s services, which included counselling and a helpline, are expected to be transferred to other support organisations.
In a statement today the HSE said that on the request of Minister Simon Harris, a very constructive meeting took place this morning involving David Hall, the Charities Regulator, representatives from the Charities sector, the HSE and Department of Health officials.
The purpose of the meeting was to discuss the ongoing issues regarding Console and how services currently being provided by Console and funded by the HSE can be continued. These services are the 24/7 Suicide Helpline, the Suicide Bereavement Liaison Service, and the Suicide Bereavement Counselling Service.
All parties at the meeting reiterated that the over-riding priority is the continuation of services to clients who are currently availing of them.
The HSE has been considering arrangements for a transition of the three services in the past number of weeks. A major part of today’s meeting was to discuss with David Hall a specific proposal for the continuation of the three services.
These discussions will continue today. It would be inappropriate to the discussions and unhelpful to the vulnerable users of the three services to make any further comment at this time.
David Hall who was installed last week to try to rescue the charity outlined spending to the High Court. He had warned Console would have to close its doors shortly if it did not get additional funding by the HSE.
He said it was costing €100,000 a month to run Console and the HSE funding amounts to just €70,000 and some €70,000 is owed to the Revenue Commisioners and there are also unknown legacy debts.
He has found no secret stash of funds which would help bail out the charity.
Former chief executive Paul Kelly, who is in a psychiatric hospital, spent lavish amounts of donations and HSE funding on his salary, cars and travel.
Console enjoyed an income of over €5m in recent years. But much of the cash was squandered using credit cards. Around €53,000 which was deposited by the HSE is all that was left in the bank account.
Interim Console CEO says ‘significant and imminent challenges’ facing charity
Another £100,000 is in the Console account in the UK.
The government has pledged to ensure the continued delivery of Console’s services.
During Leaders’ Questions at the Dáil on Thursday, Fianna Fáil’s finance spokesperson Michael McGrath asked Education Minister Richard Bruton for a guarantee that Console’s staff and services would be protected.
“Minister, can you give a commitment that the essential services Console has been providing, and continues to provide under extraordinarily difficult circumstances, will be protected and will continue to be provided?” he said.
In response, Mr Bruton said that progress had been made to ensure the protection of those services.
“I can assure you that there has been a meeting with Console, the primary motivation behind that meeting is to protect those services as the deputy said and to make sure that the workers in this service continued to be treated properly and that the service continues to be delivered.”
He added that Justice Minister Frances Fitzgerald had signed a commencement order for Part Four of the Charities Act (2009) to give the charity regulator additional investigative powers and the staffing necessary to carry out a thorough investigation.
When asked whether the troubled charity has a future, Mr Bruton said: “There isn’t a member of the house who hasn’t been touched by some family who has suffered a suicide and the dramatic impact that has on all around them.
“The support services of organisations like Console are absolutely central.
“As to whether the services will be protected within Console or within some other organisation, I think that is really the subject of discussion that I can’t give an authoritative answer on. But the core commitment and objective is to ensure that the services are protected.”

Gene test may one day predict Alzheimer’s risk in young adults

      

A GENE TEST MAY ONE DAY BE ABLE TO PREDICT THE RISK FOR ALZHEIMER’S DISEASE IN YOUNG ADULTS, A NEW STUDY SUGGESTS.

People without any thinking impairments, but with a high number of gene mutations linked to Alzheimer’s, developed worse memory over time and had a smaller hippocampus — the part of the brain associated with memory and emotion, the researchers found.
“This implies that genetic risk of Alzheimer’s disease may exert an effect on the hippocampus very early in life, which may make those individuals more likely to get Alzheimer’s disease late in life,” said lead researcher Elizabeth Mormino. She is an instructor in neurology at Massachusetts General Hospital, in Charlestown, Mass.
Although the effects were small, they offer the possibility that genetic mutations may help spot people at risk of Alzheimer’s disease decades before symptoms start, she added.
But Dr. Sam Gandy, director of the Center for Cognitive Health at Mount Sinai Hospital in New York City, said people should not be rushing out to get tested to see if they have a high risk of Alzheimer’s.
“It’s only for research at this point,” he said. “It’s potentially very useful in designing super early interventions, but not clinically useful yet.”
For the study, Mormino and her colleagues calculated a genetic risk score based on whether a person had several high-risk gene mutations. The participants, average age 75, included 166 people with dementia and more than 1,000 people withoutdementia.
In addition, Mormino’s team looked for markers of Alzheimer’s, including memory and thinking decline, disease progression and the size of the hippocampus. They also looked at links between the risk score and hippocampus size in more than 1,300 healthy 18- to 35-year-olds.
The investigators found that among older people without dementia, a higher genetic risk score was associated with worse memory and a smaller hippocampus at the start of the study, accounting for 2 percent of the total variance in memory and 2 percent of the variance in hippocampus size.
Over a three-year follow-up period, a higher risk score was tied to greater memory and thinking decline and disease progression, the researchers reported.
Moreover, the risk score was linked with overall Alzheimer’s progression. Among the 194 participants who were healthy at the start of the study, 15 developed mild thinking impairment or Alzheimer’s disease. Of 332 patients with mild thinking impairment at the start of the study, 143 developed Alzheimer’s disease, the findings showed.
With each increase in the Alzheimer’s genetic risk score, the odds of the disease progression increased nearly two times, the study authors said.
Among the younger participants, a high risk score was linked to a smaller hippocampus. However, the risk score accounted for less than 1 percent of the difference in hippocampus size between those with high and low scores, the researchers noted.
The findings were published online July 6 in the journal Neurology.
“We are starting to put the pieces of the puzzle in place that look at what these genetic risk factors might mean,” said Heather Snyder, senior director for medical and scientific operations at the Alzheimer’s Association. “It’s a first step in that direction, but it’s not ready for prime time — we still have a ways to go.”
If you have a parent or a sibling that has Alzheimer’s disease, you are at an increased risk, and “there is nothing more that a genetic test will tell you about your risk,” she said.
In the future, genetic testing might predict risk and there may be ways to stop or slow the progression of the disease, Snyder said. “But we are not there yet.”

What Do Goats, Puppies and Horses Have in Common?

GOATS COMMUNICATE WITH HUMANS USING EYE CONTACT, ACCORDING TO A NEW STUDY

   

ANYONE WHO HAS OWNED A DOG KNOWS THEY CAN SAY A LOT ONLY USING THEIR EYES. FOOD DISH EMPTY? THEY’LL LOOK UP AT THEIR HUMAN IN ANTICIPATION. WANT TO GO OUTSIDE? THEY’LL TURN THEIR HEAD TO MAKE EYE CONTACT.

Researchers thought that along with our canine companions horses were the only other domesticated animal that communicated with humans using eye contact. But a new study published in the journal Biology Letters suggests we can add one more animal to the list: goats.
Researchers from Queen Mary University conducted their study at Buttercups Sanctuary for Goats in the U.K.—an ungulate’s paradise where the resident animals receive lots of human interaction, reports Jennifer Viegas for Discovery News. The team first trained the 34 male and female goats to lift the lid on a plastic box to get at a treat. Then they created an “unsolvable problem” for the animals by sealing the box shut.
The researchers stood by as the goats tried to open the box. When they failed, the animals looked to the human experimenters as if asking for help, similar to how puppies looked back and forth between the box and person. When the researchers turned their backs, the goats did not gaze up as many times or for as long, indicating that seeing a person’s face is important.
“Goats gaze at humans in the same way as dogs do when asking for a treat that is out of reach, for example,” co-author Christian Nawroth says in a press release. “Our results provide strong evidence for complex communication directed at humans in a species that was domesticated primarily for agricultural production, and show similarities with animals bred to become pets or working animals, such as dogs and horses.”
“These results are pretty surprising,” Laurie Santos of Yale’s Canine and Primate Laboratory tells Rachel Feltman at The Washington Post. She explains that the study shows domestication for non-social reasons—goats are primarily bred for meat, milk and hides—can still produce animals with the social skills to communicate with people. “This is exciting, as it shows how little we still understand about how the process of domestication can shape rich social understanding.”
Researchers already know goats are smart and have some sort of emotional life. Previous research by the study co-author Alan McElligott showed that goats change the position of their ears and their vocalizations when feeling negative emotions. McElligott also previously showed that goats are able to learn a complex task quickly and remember how to do the same task ten months later.
Understanding the domestication process and the inner-life of goats could lead to better treatment in the future, Jan Langbein of the Leibniz Institute for Farm Animal Biology tells Discovery News. “Public knowledge about cognition in, and emotions of, farm animals will change consumers’ attitudes towards them,” he says.
These studies could also help differentiate them from their long-time, petting-zoo frenemy, sheep. “Currently there are about a billion goats on the planet being used for agriculture, but still most of the welfare guidelines for keeping them come from sheep,” McElligott tells Feltman. “Anyone who’s worked with goats and sheep know they’re quite different.”    

Saturday, July 14, 2012

Donie's Ireland news Blog Saturday


Landlord & Health Minister ‘Dr Debt’

Still gets rent from his doctors surgery

   

The Health Minister Dr James Reilly is continuing to get a rental income for his north Dublin GP surgery, it was confirmed yesterday.

Dr Reilly had a large GP practice at the Fingal Clinic in Lusk Town Centre in Dublin, where he is also landlord.
When he became a minister, he transferred the practice to Dr Susan Keenan, who now runs the surgery, which also employs doctors and nurses.
A spokesman for Dr Reilly told the Irish Independent that he was on leave of absence from the practice and the beneficiary income goes to the staff. However, Dr Reilly continues to take a rental payment.
Dr Reilly has a large list of medical card patients for whom he received an annual capitation payment and other allowances, leaving him among the highest earners in the scheme.
When he was a practising GP he rowed in with the then Health Minister, Micheal Martin, who published the individual earnings of GPs from the medical card scheme.
Dr Reilly, who earned €214,000 in annual payments from the scheme, said: “I do hope there will be no more PR stunts by the minister. I don’t want to up the ante in the row, but I think it regrettable they have tried this tactic of individualising and embarrassing GPs.”
He said the so-called “gravy train” cash was spent on paying his and his partner’s full-time doctor’s salaries, and those of an assistant and part-time doctor. It also paid for three nurses and three secretaries, running costs and a mortgage for two surgeries in north Dublin.
Meanwhile, the Cabinet sub-committee on health, chaired by Taoiseach Enda Kenny and attended by Dr Reilly, Public Service Minister Brendan Howlin and Children’s Minister Frances Fitzgerald, met yesterday to discuss the funding crisis that has seen the Health Service Executive (HSE) overrun rise to €281.6m in May.
A spokesman for Dr Reilly said it was decided to go back to the HSE and ask for a plan to be drawn up to tackle spending in areas such as agency staff, drugs, procurement, absenteeism and sick leave.
The HSE has been told not to close beds or cut admissions of patients from waiting lists. However, as hospitals struggle with a deficit of €133m, it will be impossible to avoid bed closures and a possible freeze on staff recruitment.
Dr Reilly had promised to generate more income for the HSE by making health insurers pay if one of their subscribers is put in a public bed, but this this has not yet materialised.

Bacteria is gut key to good health

‘A study shows’

          

Are you a regular “tea and toaster”, a person who habitually makes a meal out of these two items or some other restricted combination of foods? If so, you probably have an unhappy gut.

The notion that you are what you eat has taken on a whole new meaning based on research coming out of University College Cork and Teagasc. What you eat has a direct influence on what bacteria see fit to populate your gut, and the community of bacteria that live there in turn have a direct influence on your health.
Details of how this works are published this morning in the journal Nature and were released yesterday at the ongoing EuroScience Open Forum at the Convention Centre Dublin.
This community or the “gut microbiota” is an essential part of life, said Dr Paul O’Toole of UCC. “The gut biota is very important for human health. You need to think of the gut biota as an extra organ of the body.”
Clearly it must be important given there are about 10 times more bacterial cells in your gut than human cells in your entire body.
This amounts to kilos of bacteria working away happily in the gut, helping to break down food and deliver nutrients to the body.
Dr O’Toole and his colleagues, including Prof Fergus Shanahan and Dr Ian Jeffery, both of UCC, and Prof Paul Ross of Teagasc, have been exploring this community, which is most readily assessed from faecal samples.
It provides a wealth of information and can now be used to assess issues such as health, the nature of a person’s diet and whether an older person lived in the community or in long-term care.
The Eldermet project, headed by Dr O’Toole, seeks to understand the links between a person’s microbiota and general health status.
This latest study looked at the microbiota of 178 elderly people with an average age of 78.
A startling amount of information began to emerge about links between diet, level of frailty and residential status.
The research team showed that the mix of gut bacteria was linked to health status with higher levels of variety associated with better general health and lower levels of frailty.
It also indicates that having a poor mix of bacteria in the gut had long-term implications for health.
“This suggests we may be able to improve the health of older people by modifying the microbiota,” Dr O’Toole said.
There was a mix of subjects, some in long-term care facilities and some in the community. The team could predict on the basis of the microbiota present to which group the subject belonged.
There was usually a more varied bacterial mix in those living in the community. Lower variety was also correlated to frailty and poorer health, the researchers said. The lack of variety was linked in turn to a lack of variety in the diet, a condition seen as typical in the “tea and toasters”, Prof Shanahan said.
Many people ate a repetitive diet for physical or habitual reasons. But this was not enough to keep the gut bacteria happy, he said. “They [bacteria] are not parasites, but we must feed them as well. “We will all be elderly and we want to live well when elderly,” he said.

A Gene test could soon see if future lovers are compatible

  

A scientist has said the falling cost of DNA testing means Britain is on the verge of a new era of eugenics. 

It sounds like something  from a dystopian nightmare. Instead of couples settling down after falling in love with each other, they will choose their partners based on the compatibility of their genes.
According to a leading scientist, the falling cost of DNA testing means Britain is on the verge of a new era of eugenics.
Professor Armand Leroi, of Imperial College London, said that within five to ten years it will be common for young people to pay for a read-out of their entire genetic code.
The desire to have a healthy baby will then lead them to requesting to see the genetic blueprint of any prospective long-term partner.
Armed with the information, the couple could then use IVF to weed out babies with incurable diseases, a major science conference in Dublin heard.
He added that it is unlikely that people will have the ‘luxury’ of using the technology to design babies by intellect or eye colour and instead the focus will be on stopping genetic diseases.
Professor Leroi told the Euroscience Open Forum 2012 that in some ways eugenics are already here, with tens of thousands of unborn babies with Down’s syndrome and other illnesses being aborted every year.
He said: ‘These processes are very well established in most European countries.
‘Many of the ethical problems that people raise when they speak of neo-eugenics are nought once you offer gene selection or mate selection as a eugenic tool.’
Critics have hit out at the development of DNA testing. Picture posed by model
He said that the cost of genetic sequencing is falling so rapidly that ‘it is going to become very, very accessible, very, very soon’.
Lone Frank, a Danish neurobiologist, predicted some countries will embrace the idea.
‘Some cultures will say, “Let’s get a lot of genomes out on the table and see who’s got the best one”,’ she said. But she added that others will see it as an attempt to play God.
Philippa Taylor, of the Christian Medical Fellowship, said: ‘Our society’s increasing obsession with celebrity status, physical perfection and high intelligence fuels the view that the lives of people with disabilities or genetic diseases are somehow less worth living.
‘We must recognise and resist the eugenic mind set. Our priorities should be to develop treatments and supportive measures for those with genetic disease; not to search them out and destroy them before birth.’

Lafferty’s Donegal shop is buzzing as '40,000 bees move in there'

      

Staff and shoppers at a village supermarket were forced to flee the store — after 40,000 bees took up residence there.

The native black Irish honey bees set up home at the entrance to Lafferty’s Supermarket in the village of Creeslough in Co Donegal.
The shop had to close for almost four hours while experts removed them.
Supermarket owner Danny Lafferty said there were so many bees swarming around the shop, it looked like a storm cloud.
“I looked outside and I could see people waving their arms outside. It looked like it was snowing for a while,” he said.
“Then I looked closer and I could see this cloud of bees. Needless to say a lot of people were afraid to come near the shop for the afternoon while they were here,” he said.
No one was stung during the incident and Mr Lafferty called a local beekeeper, who arrived with equipment to get rid of the swarm.
“There is still a perception out that that bees sting but it rarely happens. Most bees are so full of honey that they wouldn’t have the energy,” the beekeeper said.