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Showing posts with label Volunteers. Show all posts
Showing posts with label Volunteers. Show all posts

Saturday, December 10, 2016

The Irish economy bounces back & grows 4% in third quarter of 2016

FIGURES ARE AGAIN AFFECTED BY FINANCIAL FLOWS RELATED TO MULTINATIONALS

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ON AN ANNUAL BASIS GDP WAS 6.9% HIGHER COMPARED TO THE SAME QUARTER IN 2015, WITH GNP UP 10.2%.

Ireland’s economic growth rate bounced back in the third quarter after a weak start to 2016, according to new figures from the Central Statistics Office (CSO).
However, the figures are again affected by the activities of multinationals, with a significantly slower rate of growth in the domestic economy than shown in the headline figures.
Gross domestic product (GDP) rose 4% versus the second quarter, while gross national product (GNP), which strips out the effect of multinational profit repatriations, increased 3.2%.
On an annual basis, GDP was 6.9% higher compared to the same quarter in 2015, with GNP up 10.2%. However, the latest figures were again influenced by financial flows related to big multinationals in Ireland involving the treatment of intellectual property and profit repatriations. This led to a large fall in the measured level of investment and also to a big drop in imports.
The CSO said that elsewhere investment increased, with a 3% rise in spend on machinery, led by aircraft, and a 4.6% jump in construction.
Commenting on the data, Dermot O’Leary, chief economist at Goodbody, said a more meaningful gauge than the GDP/GNP figures was core domestic demand, which shows the economy growing by about 3%; still double that of the euro zone average.
The three largest sectors of the economy experienced growth during the third quarter, with industry rising 3.8% in volume terms. Distribution, transport, software and communications increased 5.3%, while “other services” grew 1.5%.
The domestic demand?
Overall total domestic demand fell 1.8% versus the second quarter. Personal consumption, which accounts for about 53% of domestic demand, rose 0.7% in the quarter, and was running 2.1% ahead on an annual basis. Government consumption was up 0.8%.
Service exports increased €3.5 billion to €34.7 billion in the third quarter, driven by exports of computer services and business services, the CSO said. Capital investment fell 7.2% on an annual basis.
Separately, the CSO said the current account balance of payments, a measure of Ireland’s financial flows with the rest of the world, is now at an all time high of 14.7% at €10.1 billion. This compares to a surplus of €6.9 billion for the same quarter a year earlier.
Austin Hughes, chief economist at KBC, said the 4% jump in third-quarter GDP was “largely technical”. However, he added that solid gains in household spending and construction suggested healthy domestic demand.
Technical
“The outsized quarterly jump in GDP is largely technical in nature but, beyond the headline figure, the details of today’s release suggest that activity remains on a positive path, with a solid growth rate of around 4% in prospect for 2016.
“There are also signs of a more cautious consumer, continuing catch-up in construction and tentative signs of some impact from sterling weakness on goods exports,” Mr Hughes added.
Merrion’s chief economist Alan McQuaid said the National Accounts data “remain unsatisfactory”.
He said that personal spending and construction activity appeared to be holding up. However, he added that “Brexit” worries would likely intensify next year, leading to lower overall GDP growth in 2017.

The owner of the Patrick Pearse letter is to keep it in his collection abroad

THE HISTORIC DOCUMENT MAY END UP ON DISPLAY AT CULTURAL INSTITUTION

Image result for The owner of the Patrick Pearse letter is to keep it in his collection abroad  Image result for The owner of the Patrick Pearse letter is to keep it in his collection abroad
Patrick Pearse (right) with his brother, Willie, in the gardens at St Enda’s.
Patrick Pearse’s order of surrender is held by Stuart Cole, a director at Adam’s auctioneers, at their offices in Dublin, after it failed to sell at the reserved auction price.
The owner of the Patrick Pearse surrender letter which failed to sell at auction this week intends to keep it in his private collection overseas and bequeath it to his children.
The historic document may end up on display at an unspecified cultural institution in the owner’s home country, Adam’s auctioneers has said.
Retaining his anonymity, the proprietor was said to be “philosophical” about the document’s withdrawal from auction on Wednesday when bidding stopped at €770,000. It had a guide of between €1 million and €1.5 million.
The letter, written by Pearse in Easter Week shortly after his surrender to Brig Gen William Lowe, had been the focus of significant attention in the run up to its sale, prompting calls for it to be retained in Ireland.
Adam’s had made efforts to sell it on behalf of its client to the State without success. The Government said it would be an inappropriate way to spend public money and Adam’s will now apply for an export license clearing the way for it to leave the country.
“He [the owner] intends to give it to his kids at some point in the future and say, ‘you know what, here is a piece of Irish history and we are lucky to have it’,” said Stuart Cole, a director at Adam’s.
“I wouldn’t be surprised if at some time you see it being given to an institution outside of Ireland. More than likely a museum or a library.”
Mr Cole said such a move would be taken in order to protect the 100 year old letter which has spent the last 12 years in specialised storage.
The owner, described as being “of substantial means” and not motivated by profit, paid about €800,000 for the document. He is now resigned to the letter not being wanted by the State.
‘Very philosophical’
“He was very philosophical about [its failure to sell at auction]. He said either people will want it or they won’t want it.”
On Thursday, Minister for Arts Heather Humphreys said there was nothing preventing the owner donating it to the State and claiming 80 per cent of the value back in tax relief.
Under Revenue’s S1003 scheme – which encourages the donation of heritage items to Irish institutions – 80 per cent of the market value can be offset against the tax liability of the owner.
Mr Cole said, however, this would not apply to the owner of the Pearse letter as he held no business interests or tax liabilities in the State.
The anonymous collector is a frequent traveller to Ireland and decided last April, having been impressed by the Government’s handling of the 1916 centenary celebrations, it was a suitable time to sell the letter back to the country.
Mr Cole said auction was the last option but the State had shown no interest in their approaches.
Ms Humphreys told RTÉ News it was “very clear to me” that Adam’s maximised publicity to “put a very high price on this letter and they have been pressurising the State to use taxpayers’ money to purchase it”.
“The Minister is correct,” Mr Cole responded of the publicity, “my job was to work for my client and to publicise the auction as much as I could.”
He said they had approached the Government several months before the auction date “out of the limelight” to avoid bringing public pressure.

Ireland’s student unions warn against introducing a loan scheme

GRADUATES WHO EMIGRATE MAY BE ‘TOO AFRAID’ TO RETURN HOME, OIREACHTAS COMMITTEE TOLD IBEC,

Image result for Ireland's student unions warn against introducing a loan scheme  Image result for Ireland's student unions warn against introducing a loan scheme

HOWEVER, THEY TOLD THE COMMITTEE THAT AN INCOME-CONTINGENT LOAN SYSTEM WAS THE ONLY “EQUITABLE AND SUSTAINABLE” OPTION.

Thousands of graduates will end up leaving Ireland and may never return if a student loan scheme is introduced, an Oireachtas committee heard on Thursday.
An income-contingent loan system – where graduates pay fees when their earnings reach a certain level – is one of a number of options proposed in a Government-commissioned report into the future funding of higher education.
However, Jane Hayes-Nally, president of the Irish Second-Level Students’ Union, said many graduates from New Zealand were “too afraid” to return home since it introduced a loan scheme.
“Is this what will happen to me? Too afraid to come home, struggling to make repayments, saddled with debt before I am even 25,” she asked.
The fifth-year secondary school student said income-contingent loans would end up driving students overseas to countries such as Germany where third level is publicly funded.
“My only option could be to enrol in Germany. Right now, no fees apply to international students in Germany, bar a small contribution of €50. So for the class of 2016, willkommen Deutschland.

A RADICAL IDEA.

Other student representative bodies, including the Union of Students of Ireland (USI) and Trinity College Dublin Students’ Union, also called on committee members to support a publicly-funded higher-education system.
Annie Hoey, USI president, said a publicly-funded system was not a radical idea and that “fully-free” education was available in Scotland, Scandinavia and Germany.
Universities and employers’ groups, however, were generally supportive of a loan scheme as the most realistic way of providing the kind of funding needed to tackle a “crisis” facing the sector.
Employers’ group Ibec said a publicly-funded system was not economically sustainable or socially desirable.
Tony Donohoe, Ibec’s head of education, said an income-contingent loan system was the only “equitable and sustainable” option.
Such a model needed to avoid mistakes made in other countries, he said.
“It would be economically foolish and socially unacceptable to saddle a generation of young people with the scale of debt that we see in the US and will probably see in the UK,” he said.
“Therefore, we need a balanced, fair and sustainable system that combines adequate State investment with an affordable student contribution.”

A STRUCTURED APPROACH?

He said business currently contributed €360 million a year through the National Training Fund – a levy on employers – and individual companies contributing directly to colleges.
Mr Donohoe said employers were willing to play their part through more effective use of the National Training Fund and a structured approach to supporting programmes in areas of skills demand.
The chair of NUI Galway’s governing body, former Supreme Court judge Catherine McGuinness, said that while she would like a State-funded system, it was not realistic and student loans seemed “the best solution”.
She said the “free fees” system introduced 20 years ago had not led to a significant narrowing in the social divide.
“We can at least see if we can design a system that does not let the State or employers off the hook,” she said.

Government’s ‘Creative Ireland’ plan is outlined by Taoiseach

TAOISEACH LAUNCHES FIVE-YEAR PROGRAMME TO PROMOTE CULTURE AS PART OF EVERYDAY LIVES

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THE TAOISEACH ENDA KENNY AT THE NATIONAL GALLERY OF IRELAND SAID: “WE CAN MAKE IRELAND THE FIRST COUNTRY IN THE WORLD TO GUARANTEE ACCESS FOR EVERY CHILD TO TUITION AND PARTICIPATION IN ART, MUSIC, DRAMA AND CODING.

There was a broad welcome across the arts and culture sectors for the Government’s new five-year plan, Creative Ireland, which was launched by the Taoiseach in the newly refurbished Shaw Room at the National Gallery of Ireland on Thursday.
In front of an audience which included the heads of most of the State’s key cultural institutions, Mr Kenny outlined an ambitious vision for what he described as “placing culture at the centre of our lives, for the betterment of our people and for the strengthening of our society”.
The Taoiseach, along with Minister for Arts Heather Humphreys and Minister for Public Expenditure and Reform Pascal Donohoe, laid out the details of the cross-governmental initiative, which aims to build on the legacy of the Ireland 2016 centenary programme.
The Taoiseach himself will chair a new Government committee dedicated to achieving the objectives of the plan, while a dedicated programme office will be set up within the Department of Arts.

COMMITMENTS ANNOUNCED FOR THE NEXT 12 MONTHS INCLUDE:

* a pilot scheme to assist self-employed artists who have applied for Jobseekers Allowance;
* a new annual cultural day, to be held nationwide on Easter Monday each year; and
* the appointment of a culture team by every local authority in the country.

HERITAGE INFRASTRUCTURE IN IRELAND?

Plans will be drawn up for an investment programme for Ireland’s cultural and heritage infrastructure and institutions, as well as for developing Ireland as a global hub for film, TV drama and animation. The first item on the agenda, however, is the drafting of a five-year “Creative Children” plan, which will “enable every child to access tuition in music, drama, art and coding”.
“Together we can do extraordinary things,” Mr Kenny said at the launch. “We can make Ireland the first country in the world to guarantee access for every child to tuition and participation in art, music, drama and coding. We can make every local authority a dynamic hub of cultural creativity.
“We can unlock the huge potential of our people in the creative industries. And we can make an important statement to ourselves and to the world about the interdependency of culture, identity and citizenship.”
Mr Donohoe said the Government recognised that high-quality infrastructure was critical for a vibrant arts and culture sector. Investment in culture underpinned social cohesion and supported strong and sustainable economic growth.
Culture and citizenship
Ms Humphreys said the initiative had been inspired by the “extraordinary public response” to the 1916 Centenary Programme. “This year thousands of cultural events were held around the country,” she said. “Bringing people together in shared reflections on identity, culture and citizenship that combined history, arts, heritage and language. We now want to build on the success of the commemorations and plan ambitiously for our arts and culture sectors for the years ahead.”
Ms Humphreys described the plan as “a very ambitious public policy initiative; possibly the most significant for the arts and cultural sectors in a generation”.
The plan was welcomed by the director of the National Library of Ireland, Dr Sandra Collins, who described it as “progressive and exciting”.
The National Campaign for the Arts, a nationwide, volunteer-led movement, said the plan had “the potential – if delivered – to realise a sea-change for the cultural sector but also for the wellbeing of Irish society as a whole” and welcomed the proposed social protection changes as a “a long overdue safety net for self-employed artists” .

Ireland and Sligo hosts as European Capital launch of Volunteering campaign for 2017 in January 2017

Image result for Sligo Capital of Volunteering campaign for 2017 in January 2017  Image result for Sligo hosts European Capital of Volunteering campaign for 2017 in January 2017   Image result for Sligo Fleadh Volunteers of 2015

SLIGO IS TO STAGE A SPECTACULAR OPENING CEREMONY TO KICK OFF ITS YEAR AS EUROPEAN VOLUNTEERING CAPITAL 2017, WITH ACCLAIMED MUSICIANS AND VOLUNTEERS TAKING CENTRE STAGE AT A FRIDAY, JANUARY 27 , 2017 CIVIC AND GALA EVENT.

The designation of European Volunteering Capital 2017 was formally bestowed on Sligo at an event held in London’s City Hall on Dec 5.
The EVC 2017 designation is a coup for Sligo in that it follows the major European cities of Barcelona, Lisbon and London in being chosen to showcase volunteering and the positive impacts that it has on lives across Europe.
The gala celebration at the IT Sligo Knocknarea Arena will feature VIP guests and specially composed pieces by acclaimed musician Michael Rooney.
The ‘Spirit of Sligo’ celebration event will also feature a selection of inspiring volunteer stories and performances by other artists including Niamh Crowley, Kieran Quinn, Sligo Gospel Choir and the Sligo Academy of Sinfonietta Orchestra.
Highlights from Michael Rooney’s rousing compositions Famine, Battle of the Books, De Cuellar and Macalla suites will be performed alongside a new arrangement of his seminal Prince Charles Suite by traditional and classical musicians.
Ciara Herity of Sligo Volunteer Centre said: “The designation is a real honour and a chance to tell the many stories of volunteerism which happen every day in Sligo and beyond.
“London showed in 2016 what was possible in connecting people to volunteering and next year we hope to emulate that work by showcasing Sligo at its very best.”
Those sentiments were echoed by Ciaran Hayes, CEO of Sligo County Council, who attended the launch of the January 27 ‘Spirit of Sligo’ gala event.
He said: “The ‘Spirit of Sligo’ gala event is a wonderful not to be missed show. It’s also a recognition and celebration of all of those who give back to their community, the silent majority who contribute so much to Sligo and who make us what we are.
“The range and extent of volunteering and generosity of volunteers in this county is breathtaking. It’s a special and remarkable place to live and I’m delighted that we can now bring those stories to life and bring the real Sligo to the fore with such a spectacular and entertaining opening.”

Say what you like? But monkey mouths and throats are equipped to talk like us

Image result for monkey mouths and throats are equipped to talk like us   Image result for monkey mouths and throats are equipped to talk like us

MONKEYS’ VOCAL EQUIPMENT CAN PRODUCE THE SOUNDS OF HUMAN SPEECH, RESEARCH SHOWS, BUT THEY LACK THE CONNECTIONS BETWEEN THE AUDITORY AND MOTOR PARTS OF THE BRAIN THAT HUMANS RELY ON TO IMITATE WORDS.

If you could change the way a monkey or an ape’s brain is wired, that animal would be capable of producing perfectly intelligible speech.
That’s the conclusion of a study that closely tracked the movements of a monkey’s mouth and throat with X-rays, to understand the full potential of its vocal tract.
The researchers used X-ray videos to capture and trace the movements of the different parts of a macaque’s vocal anatomy — such as the tongue, lips and larynx — during a number of typical macaque behaviors, including lip-smacking, yawning, grunting and cooing.
Researchers then used that information to create a computer model of what it would sound like if the monkey were able to say phrases such as “happy holidays.”
Monkey Voice Simulation Saying “Happy Holidays”
The finding calls into question long-held assumptions about how humans developed their unique ability to use spoken language.
“What you’ll find in the textbooks is that monkeys can’t talk because they don’t have the appropriate vocal tract to do so,” says Tecumseh Fitch, a cognitive biologist at the University of Vienna. “That, I think, is a myth. My colleagues and I all get very tired of seeing this. But you see it in all the textbooks. Lots of popular books, and also scholarly books about the evolution of language, assume that in order to evolve speech we had to have massive changes in our vocal tract. ”
In the past, scientists looked at dead animals to judge what their vocal tracts could do. But Fitch says that made people vastly underestimate the flexibility of nonhuman mammals.
He and his colleagues monitored a long-tailed macaque named Emiliano as he made a wide range of different gestures and sounds, including lip-smacks, yawns, chewing, coos and grunts. Their special equipment took a rapid series of X-rays that allowed them to capture the full range of movement in the monkey’s vocal tract. Then they used computer models to explore its potential for generating speech.
Friday, in the journal Science Advances, his team reports that monkeys would be physically capable of producing five distinguishable vowels — the most common number of vowels found in the world’s languages.
And human listeners could clearly understand phrases they created with their synthesized monkey speech, including a marriage proposal.
Monkey Voice Simulation Saying “Will You Marry Me?”
The bottom line, says Fitch, is that a monkey’s speech limitations stem from the way its brain is organized.
“As soon as you had a brain that was ready to control the vocal tract,” Fitch says, “the vocal tract of a monkey or nonhuman primate would be perfectly fine for producing lots and lots of words.”
The real issue is that monkeys’ brains do not have direct connections down to the neurons that control the larynx and the tongue, he says. What’s more, monkeys don’t have critical connections within the brain itself, between the auditory cortex and motor cortex, which makes them incapable of imitating what they hear in the way that humans do.
Rise of the Planet of the Apes, a science fiction movie from 2011, actually has the right idea, notes Fitch. In that film, after a lab chimp named Caesar undergoes brain changes, he eventually is able to speak words such as “No.”
“The new Planet of the Apes is a pretty accurate representation of what we think is going on,” says Fitch.   

Saturday, June 25, 2016

Donie's Ireland daily news BLOG.

IDA set to negotiate with UK companies to relocate to Ireland after Brexit vote

THE AGENCY IS TO BEGIN NEGOTIATIONS WITH COMPANIES LOCATED IN UK THAT MAY WANT TO RELOCATE TO IRELAND.

   

MARTIN SHANAHAN (picture left), THE CHIEF EXECUTIVE OF IDA IRELAND, SAYS THE STATE AGENCY WILL SOON BEGIN NEGOTIATIONS WITH BANKS AND OTHER COMPANIES LOCATED IN THE UK THAT MAY WANT TO RELOCATE TO IRELAND FOLLOWING THE BREXIT VOTE.

Martin Shanahan, the chief executive of IDA Ireland, says the State agency will soon begin negotiations with banks and other companies located in the UK that may want to relocate to Ireland following the Brexit vote.
Mr Shanahan stressed his first preference was for Britain to remain within the European Union (EU), but he said the IDA has “done its homework” on how to maximise foreign investment for Ireland now that the UK has voted to leave.
“We have been in discussion with potential clients [who may choose to relocate to Ireland from the UK] for months. They approached us,” said Mr Shanahan. “We have a good view on the potential for Ireland.
He said discussions with potential foreign investors could begin as soon as “next week, or the week after”.
IDA’s existing 1,200 client companies are “still digesting the news”, he said. Mr Shanahan yesterday wrote to the 1,200 to say Ireland remains committed to the EU and is effectively still open for business.
He said Ireland’s “stability” would be an attractive feature when attracting new investment in the midst of the uncertainty created for the UK by the vote. Mr Shanahan also agreed that financial services and technology were two sectors where Ireland would be particularly well placed to pick up fresh foreign investment that might otherwise locate in the UK.
“But we intend to push for investment right across the portfolio, including life sciences and engineering,” he said. “Our mandate prior to Brexit was to maximise investment for Ireland, and nothing has changed in that regard.”

TERMS OF EXIT?

Fergal O’Brien, chief economist at the employers’ lobby Ibec, said the UK is now likely to “become more aggressive” in securing foreign investment to protect its economy, which could increase competition faced by the IDA.
He said a lot depends on the terms of the exit deal given to the UK, including its level of access to the EU’s internal market: “It is in Ireland’s interests to get as much stability as possible for the UK.”
Mr O’Brien suggested that while other EU states might want to impose tough measures on the UK to discourage other countries from exiting, Ireland “needs to establish at EU level that we have skin in the game” and push for leniency.
Enterprise Ireland, meanwhile, warned against the effects of exchange rate volatility for Irish exporters into the UK. It said it would also support Irish exporters to devise medium-term diversification plans.
“In addition to our team in the UK, we have put in place a dedicated email address, phone-line and team for Enterprise Ireland clients to respond to their immediate concerns and issues,” said the agency.

Ryanair and Aer Lingus could be hit by fall in passengers

INTERNATIONAL AIR TRANSPORT ASSOCIATION SAYS WEAKER STERLING MAY CUT NUMBER OF UK TRAVELLERS

   

IAG SAID IT NO LONGER EXPECTS TO GENERATE AN ABSOLUTE OPERATING PROFIT INCREASE SIMILAR TO 2015.

Ryanair and Aer Lingus parent, International Airlines’ Group (IAG), could be hit by a fall in UK passenger numbers following the Brexit vote, according to a leading industry body.
The International Air Transport Association (IATA) predicts that a weakened sterling and shrinking economy could cut UK airline passenger numbers, which hit 250 million last year, by 3 to 5% by 2020.
A report the association published yesterday shows that Ryanair and IAG, owner of Aer Lingus, are amongst the airlines that are most exposed to a fall in air travel.
The UK is one of Ryanair’s biggest markets, accounting for more than 30 million of the 100-plus million passengers that it flies every year.
This gave it a large share of the 117 million people that flew between the UK and the rest of the EU last year. It also employs 4,000 people there.
IAG’s other airlines include British Airways, which carried more than 43 million people last year. The group warned in a statement following the vote that it does not expect this year’s growth in operating profits to match that of 2015.
Ryanair’s chief marketing officer, Kenny Jacobs, said that the Irish company would campaign to have the UK remains in the EU’s Open Skies regime, which allows airlines to fly freely between member states.
However, he indicated that Ryanair is more likely to spend money on countries within the EU, such as the Republic, Germany, Spain and Italy. “It’s going to mean that when we are looking at investing, we will look outside the UK,” he said.
The vote sent travel stocks tumbling. IAG fell 22.54% to 409 pence sterling in London. Ryanair shares were down 11.77% at €12.07 in Dublin.
Shaun Quinn, chief executive of State body, Fáilte Ireland, responsible for promoting tourism to the Republic, said it was too early to speculate on the likely impact of the vote on the industry.
“Fáilte Ireland will be monitoring any short term impacts of a devalued sterling on tourist numbers to Ireland and working with businesses in the sector to develop strategies to address any arising competitiveness challenges,” he said.
The Irish Hotels Federation warned that there was a risk a risk that economic uncertainty and a weaker sterling would hit visitor numbers from the UK.
Republic attracts three million tourists from Britain every year. The hospitality industry fears that this number could decline as the Brexit fallout continues.

Sligo seeking funding as European Volunteer Capital

Sligo, Ireland, Finds Working Capital in Its Couch Cushions     

CONCERN HAS BEEN EXPRESSED THAT NO FUNDING HAS YET BEEN ARRANGED FOR SLIGO’S DESIGNATION AS EUROPEAN VOLUNTEERING CAPITAL 2017.

The manager of Sligo Volunteer Centre Ciara Herity told councillors last week that while the supports from the Municipality were in place, no concrete funding was secured.
“We are the first non-country capital winner. It’s very exciting, for Sligo and for Ireland. The uniqueness of Sligo winning is that we are a small rural county on the periphery of Europe. It’s a privilege to have it,” she said.
Cathaoirleach of the County Council Cllr Rosaleen O’Grady said she was “concerned that they’ve no funding” but added that they had “the right woman in Marian Harkin in Europe” to help them source funding.
The MEP is Patron of Sligo Volunteer Centre and attended the presentation in person last week.
Sligo beat seven other cities in the running for the 2017 designation and previous winners include London, Lisbon and Barcelona.
Sligo Volunteer Centre celebrates its 10 year anniversary in 2017 and the designation will give due recognition to that.
M/s Herity said the designation would bring more European visitors here along with an economic boost to the town and county.
It’s hoped Sligo will host some national events: Volunteer Ireland, Special Olympics, Foroige and the Irish Girl Guides have been approached about hosting events here next year.
Cllr Sean MacManus said it was “a fantastic achievement for a small county on the periphery of Europe”. He said it was going to be difficult to match London and Lisbon “especially in view of the fact that we’ve no funding.”
“Even given Sligo County Council’s straitened financial situation to include some forming of funding to back them up,” he said.
Cllr Sinead Maguire also congratulated Sligo Volunteer Centre and said “It does reflect the spirit of volunteering that we have here in Sligo. We’re worthy winners.”
Council Chief Executive Ciarán Hayes is now tasked with designing a programme of events, actively pursuing sponsorship and raising awareness.

Marked reduction in PSA testing

 Pictured left to right at the John Fitzpatrick Irish Prostate Cancer Conference in Dublin were: Mr Killian Walsh, Prof Michael Blute, Mr Peter Ryan and Mr Andrew Fitzpatrick   

A US TASK FORCE RECOMMENDATION AGAINST PSA-BASED SCREENING HAD A MAJOR EFFECT, GARY CULLITON HEARD AT THE JOHN FITZPATRICK IRISH PROSTATE CANCER CONFERENCE. SINCE THIS POLICY DECISION WAS MADE, THERE HAS BEEN A CONSIDERABLE IMPACT ON RATES OF DETECTION

Policy decisions are rapidly influencing primary care practice in the US. There has been a decrease in prostate-specific antigen (PSA) screening, and the urology response has been an increase in the use of active surveillance in men with low-risk disease. Recent years have also seen the advent of surgical cohorts with more intermediate and high-risk disease.
A recommendation against PSA screening may be leading to later stage disease at diagnosis, a meeting in Dublin has heard.
There has been a shift toward more advanced disease at diagnosis, and decreased use of PSA-based screening may worsen this trend.
The rapid decrease in PSA use was concerning, said Prof Michael Blute, Chief of Urology at Boston’s Massachusetts General Hospital and Professor of Surgery at Harvard. This would continue until there was a change at policy level, he said, in a talk on policy decisions and the changing face of prostate cancer at the John Fitzpatrick Irish Prostate Cancer Conference in Dublin recently. His talk dealt in particular with diagnosis and management in the US.
More surgical patients are seen with advanced or adverse pathology. “My hope is that smarter prostate cancer screening methods will be introduced,” said Prof Blute. One of his concerns centres on “reaching primary care practices.”
In 2012, the US Preventive Services Task Force (USPSTF) recommended against PSA-based screening for prostate cancer. There was moderate or high certainty that the service had no net benefit or that the harms outweighed the benefits, said the Task Force, which discouraged use of the service.
Since this policy decision was made, there has been a major impact on rates of detection. Urologists order between 7 and 10 per cent of the PSA tests in the country. The vast majority of PSA tests are ordered by primary care practices.
Dramatic reduction
A dramatic reduction was seen in the utilisation of PSA testing in primary care practices (Ahmedin Jemal, 2015). There were then conflicting results from the PLCO and ERSPC trials and the case against screening appeared to strengthen.
Following the 2012 USPSTF recommendation, there has been a 20 per cent reduction in the use of PSA testing in the United States and rates would continue to fall, said Prof Blute. “The argument about PSA screening became an ‘all or none’ debate. The ‘none’ side won out. This is having a significant impact for men diagnosed with prostate cancer at our practice.”
Overall incidence among the cohort of men aged 50 and older in the US dropped off in 2012. However, the presentation stage — for localised disease or metastatic disease — has not changed; it lags behind. For the first time in two decades, the incidence of metastatic disease among men aged 75 years or older is starting to creep up.
“My fear is that primary care practices are not listening to American Urological Association (AUA) guidelines. They are not listening to National Comprehensive Cancer Network (NCCN) guidelines. They are listening to the USPSTF,” Prof Blute said.
Since the 2012 USPSTF recommendation, there has been a 28 per cent reduction in the diagnosis of prostate cancer in the US (Barocas DA, J Urol, 2015). Equal reductions have been seen in the diagnosis of men with low-, intermediate- and high-risk cancers. “This is an extremely rapid change and it is a real concern for men with intermediate- or high-risk disease who will experience delay in diagnosis,” said Prof Blute. Delayed diagnoses would be a feature and an increase in the incidence of men with metastatic disease at diagnosis was sure to follow, he said.
The recommendation has been associated with decreased PSA screening in all age groups, decreased rates of prostate biopsies and decreased incidence of prostate cancer. There has been no change in the distribution of low-, intermediate- and high-grade disease. There have been no changes thus far among men aged between 50 and 74. Increases in men presenting with metastatic disease 75 years and older are now seen (Ahmedin Jemal, 2015). Men in the 50-to-70 years bracket would have a similar response if there was continued reduction in the utilisation of PSA, Prof Blute predicted. An increase in absolute and relative amounts of late stage prostate cancer would be seen, he predicted.
Increased numbers.
A hugely increased number of men with low-risk disease were identified following the introduction of PSA testing.
Seventy-to-80 per cent of the diagnoses were low-risk. Now, almost 40 per cent of men with newly diagnosed prostate cancer are placed — appropriately — in active surveillance protocols (National Cancer Database, 2004 to 2013).
Between 2004 and 2012, intermediate- and high-risk men were increasingly seen among surgical cohorts. Low-risk men may not benefit from aggressive therapy, but because of progression or repeat sampling biopsies that reveal higher grade disease in 20 per cent of cases, men may be upstaged to intermediate risk disease.
Data covering private practice urology in the US showed a drastic reduction in use of ADT monotherapy for patients with the highest risk on Cancer of the Prostate Risk Assessment (CAPRA) score after 2004 (Cooperberg, JAMA, 2009). Use of radical prostatectomy more than doubled. There was a continued reduction in primary androgen deprivation therapy as monotherapy among men aged 75 and older. There was also an increase in the utilisation of more aggressive therapy for patients who had higher-risk disease.
Pathologically, there has been a reverse stage shift: operations have been performed on more men with higher-risk disease. From 2000 to 2010, the number of men who underwent radical prostatectomies for low-risk disease, dropped drastically — from 50 to 30 per cent (Silberstein, Cancer, 2011). By contrast, the number of men with high- and intermediate-risk disease increased. More and more men with adverse pathology results would be seen following radical prostatectomy, said Prof Blute.
The number of men operated on with organ-confined disease was falling, but more men with extra-prostatic disease were seen.
However, there was a reduction in operations on men with primary pathologic Gleason Score Six disease.
Low-risk tumours are more frequently treated with active surveillance in the US, while high-risk tumours are more frequently treated with surgery. The recommendation against PSA screening is leading to a reverse Stage migration.
Prof Blute spoke about the role of MRI in surgical management of prostate cancer. There would be an increased tendency to operate on more aggressive tumours. Some cancer cells may be left behind (increased positive surgical margin rates) and there would probably be less favourable cancer control outcomes locally — particularly where surgery was used as single-modality treatment. Use of adjuvant therapies and pelvic lymph node dissection would also increasingly be considered.
Men in the high-risk cate-gory are a heterogenous group. Those with high-risk disease who have a single adverse variable do better than men with multiple adverse variables. In terms of management, surgery is included in guidelines by the National Comprehensive Cancer Network (NCCN) for cases of resectable disease, but unlike breast or colorectal cancer, algorithm surgery has not been tested in a multimodal fashion with radiation and hormone therapy.
Where surgery is used for initial management in high-risk disease, overall 10-year cancer-specific survival is 80-to-90 per cent (Stewart, 2015). Many men do well, where their high-risk disease is managed using surgery. Fifteen-year outcomes were published on a series of men with clinical T3 disease who had operations. The complication rate among these men — who underwent wide local excision of their cancers — was studied. They had good outcomes — equivalent to T2 disease. In terms of urinary control, 80 per cent of these men were completely dry (Ward, 2005, BJUI).
MRI is used to stage these patients prior to surgery. The same techniques used in low-risk men cannot be used to operate on men with high-risk disease. Extended pelvic lymph node dissections are recommended as the node positive rate for high risk disease will be 10 to 15 per cent. There would be risk associated with dividing the lateral pelvic fascia and releasing the neurovascular bundle and not achieving negative surgical margins. Therefore, an extrafascial approach is favoured for men with high-risk disease.
An objective was to elevate the rectoprostatic fascia so there was a wide surgical margin in the patient, said Prof Blute.
Using wide local excision surgery as an initial treatment among 1,800 men with high risk disease, 57 per cent of men ultimately had pathologically organ-confined disease and did well (Boorijian, J Urol, 2008). Ten-year local recurrence-free survival was 90 per cent. Local recurrence-free survival in these men (who often had at least T3 disease) was equivalent to that in men with T2 disease.
Profiling
Increasingly, a biomarker has been used. The Decipher test is a genomic classifier. Some 545 Mayo Clinic patients with high-risk disease were selected following radical prostatectomies (Erho, Crisan, PLOS One, 2013). These men had biochemical recurrence and a test was sought that would predict metastases.
Some 192 cases developed metastases. Transcriptome-wide expression profiling was carried out to identify signalling pathways associated with metastases.
If the Deci¬p¬her score indicated a low risk, only 2.4 per cent of men ultimately demonstr-ated metastases. The genomic classifier was judged to yield independent prognostic information in a multivariable analysis. The Decipher test was found to be the only significant variable for detecting rapid metastases and it performed well, compared to the CAPRA-S and Stephenson nomograms (Klein, Euro Urology 2015).
The Decipher test provided additional stratification in terms of risk (Ashley Ross, Johns Hopkins). Molecular stratification has been needed to classify men with high-risk disease better. There is a concern about additional toxicities in these men (who have undetectable PSA, are responding well to their surgery and have good quality of life).
Multivariable analysis demonstrated that genomic high-risk men, who received ART, had higher metastases-free survival, compared to salvage radiation treatment. An 80 per cent reduction in risk of metastases was demonstrated, among the Decipher high-risk group getting ART — rather than salvage — therapy.
Metastates
This would hopefully inform the debate about the timing of radiation treatment in the post-op setting, said Prof Blute. The genomic classifier would be very helpful in men who had high risk disease. Data showed that significant numbers of men with adverse pathologies did not develop clinical metastases. They do well and do not need adjuvant therapies.
Introducing a genomic classifier for this group of men would be very valuable in stratifying who needed the therapies and when. In patients with adverse pathology and a low-risk genomic classifier result, a careful eye should be kept on the PSA results, data indicate. More prospective studies were required, said Prof Blute.
In the current era, aggressive treatment of localised prostate cancer was increasingly being reserved for those men who needed it the most, and active surveillance for men with low-risk disease.
In the future, surgical cohorts would be increasingly intermediate- and high-risk patients, and focus must be on managing adverse pathology after surgery to achieve long-term local control of prostate cancer, added Prof Blute.

Crops grown on Mars soil are safe to eat

   

ECOLOGIST WIEGER WAMELINK INSPECTING THE PLANTS GROWN ON SOIL SIMILAR TO THAT ON MARS AT THE WAGENINGEN UNIVERSITY.

Results from trials using soil like that on Mars hold promise for future settlements on planet
Dutch scientists said crops of four vegetables and cereals grown on soil similar to that on Mars have been found safe to eat, amid plans for the first manned mission to the planet.
Abundant harvests of radishes, peas, rye and tomatoes all grown on the soil were found to contain “no dangerous levels” of heavy metals, said the team from Wageningen University on Thursday.
“These remarkable results are very promising,” said senior ecologist Wieger Wamelink. “We can actually eat the radishes, peas, rye and tomatoes, and I am very curious what they will taste like.”
Future Mars settlers will have to take food supplies with them and then plant crops in order to survive.
So using soil developed by Nasa to resemble that of the Red Planet, the university in the Netherlands has been experimenting since 2013 and has managed to raise 10 crops.
There is uncertainty still about their absorbing the high levels of heavy metals such as cadmium, copper and lead present in Mars soil. Further tests are needed on the other six crops, including potatoes, in research being backed by a crowd-funding campaign.
Nasa plans a manned trip to Mars within the next 10 to 15 years or so, and similar projects are being pursued by US billionaire Elon Musk and Dutch company Mars One, tentatively aiming to set up human colonies on the Red Planet.
The Mars One project has backed the Wageningen work and is deciding on the final 40 out of 100 candidates hoping to be its astronauts.
But unlike any Nasa mission, Mars One is a one-way trip: Whoever joins this journey to the foreign world is never, ever coming back to Earth, Fox 5 News reported.
Mars One CEO Bas Landsdorp estimates the project will cost US$7 billion (S$9.5 billion). He plans to pay for it in part by turning the mission into a reality show.
But space expert Neil deGrasse Tyson is sceptical.
“I try not to get in anybody’s way who is dreaming big,” he told Business Insider after Mars One announced the project in February last year. “But I’m sceptical it can be accomplished on the timescale” given.